The fourth edition of the Greater Mekong Subregion (GMS) statistical database booklet produced by the GMS Secretariat, Southeast Asia Regional Department, Asian Development Bank (ADB), includes two new chapters, tourism and health. The tourism chapter includes data on tourist arrivals by regional origin and transport mode; bilateral tourist exchanges within the subregion; supply-side and macro indicators of the sector. The health chapter covers demography-related health data; basic health and/or sustainable development goals—related indicators; access to medical workers; and several measures of current health expenditures. Data in the energy chapter have been completely revised: new data sources were used and a longer time series was constructed for all GMS members; moreover, additional energy consumption indicators were added. The chapter on structure of merchandise trade has also been updated.